For years, scientists and physicians have known that mRNA-based COVID-19 vaccines, while remarkably effective and broadly safe, carry a small but real risk of causing myocarditis — inflammation of the heart muscle — particularly in young men and adolescents. Now, a research team at Stanford Medicine has identified the precise biological mechanism behind this phenomenon, offering not only a clearer scientific picture but also a potential path toward preventing the condition altogether.
The findings, published in Science Translational Medicine, represent a significant step forward in understanding how the immune system can, in rare cases, turn its powerful defenses against the very organ it is meant to protect.
A Rare but Real Risk
COVID Vaccine and Pregnancy – CentraState Healthcare System
Before diving into the science, it is worth putting the risk in perspective. mRNA COVID-19 vaccines have been administered several billion times worldwide and have been scrutinized extensively for safety. The rate of vaccine-associated myocarditis after a first dose is approximately one in every 140,000 people vaccinated. That figure rises to roughly one in 32,000 after a second dose. Among male vaccinees aged 30 and under — the group most affected — the rate climbs to about one in 16,750.Continue reading…
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